Unlocking Zeptomolar Single-Molecule Detection by Synergizing Digital Microfluidics and Digital CRISPR

Z Zheng Li F Fenggang Li (Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering) L Liyan Hua (Shaoguan Maternal and Child Health Hospital) F Fengli Chai (Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering) L Liming Xie (CAS Key Laboratory of Standardization and Measurement for Nanotechnology) D Dou Wang (Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering) S Shuailong Zhang (School of Integrated Circuits and Electronic, Engineering Research Center of Integrated Acousto-optoelectronic Microsystem (Ministry of Education of China)) C Chunmiao Zheng (School of the Environment and Sustainable Engineering) Z Zuankai Wang X Xingyu Jiang (School of Chemistry and Molecular Engineering)

Article Details

Volume / Issue Vol. 147, Issue 47
Published November 26, 2025
Pages 43870-43883
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

Z

Zheng Li

F

Fenggang Li

Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering

L

Liyan Hua

Shaoguan Maternal and Child Health Hospital

F

Fengli Chai

Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering

L

Liming Xie

CAS Key Laboratory of Standardization and Measurement for Nanotechnology

D

Dou Wang

Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering

S

Shuailong Zhang

School of Integrated Circuits and Electronic, Engineering Research Center of Integrated Acousto-optoelectronic Microsystem (Ministry of Education of China)

C

Chunmiao Zheng

School of the Environment and Sustainable Engineering

Z

Zuankai Wang

X

Xingyu Jiang

School of Chemistry and Molecular Engineering