Understanding interspecies drug response variations between human and rodent P2X7 receptors

C Chang-Run Guo D Danqi Sheng J Ji-Yuan Li T Tian-Tian Li J Jia-Bao Yao R Rui Zhang Y Ye Huang (Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Diseases, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University) Y Ying-Ying Zhao D Dong-Ping Wang (Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University) J Jie Chen J Jian Li J Jiang Wang (Synthetic Molecule Design and Development, Lilly Research Laboratories) Y Yu Zhou C Cheng Shen F Fei Jin P Peng Cao M Motoyuki Hattori (State Key Laboratory of Genetics and Development of Complex Phenotypes, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University) H Hong Liu Y Ye Yu (State Key Laboratory of Precision and Intelligent Chemistry, Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science)

Article Details

Volume / Issue Vol. 16, Issue 1
Published December 02, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

C

Chang-Run Guo

D

Danqi Sheng

J

Ji-Yuan Li

T

Tian-Tian Li

J

Jia-Bao Yao

R

Rui Zhang

Y

Ye Huang

Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Diseases, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University

Y

Ying-Ying Zhao

D

Dong-Ping Wang

Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University

J

Jie Chen

J

Jian Li

J

Jiang Wang

Synthetic Molecule Design and Development, Lilly Research Laboratories

Y

Yu Zhou

C

Cheng Shen

F

Fei Jin

P

Peng Cao

M

Motoyuki Hattori

State Key Laboratory of Genetics and Development of Complex Phenotypes, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University

H

Hong Liu

Y

Ye Yu

State Key Laboratory of Precision and Intelligent Chemistry, Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science