Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics

M Martin Steger G Gisele Nishiguchi (Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics) Q Qiong Wu (State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology) B Bjoern Schwalb B Bachuki Shashikadze K Kevin McGowan (Medicinal Chemistry Center, Department of Chemical Biology and Therapeutics) M Marisa Actis (Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics) A Anup Aggarwal (Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics) Z Zhe Shi J Jeanine Price A Anand Mayasundari (Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics) L Lei Yang A Anastasia H. Bednarz S Sophie Machata T Tobias Graef D Denis Bartoschek V Vadim Demichev U Uli Ohmayer J Jun Yang H Henrik Daub Z Zoran Rankovic

Article Details

Volume / Issue Vol. 16, Issue 1
Published August 20, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (21)

M

Martin Steger

G

Gisele Nishiguchi

Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics

Q

Qiong Wu

State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology

B

Bjoern Schwalb

B

Bachuki Shashikadze

K

Kevin McGowan

Medicinal Chemistry Center, Department of Chemical Biology and Therapeutics

M

Marisa Actis

Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics

A

Anup Aggarwal

Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics

Z

Zhe Shi

J

Jeanine Price

A

Anand Mayasundari

Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics

L

Lei Yang

A

Anastasia H. Bednarz

S

Sophie Machata

T

Tobias Graef

D

Denis Bartoschek

V

Vadim Demichev

U

Uli Ohmayer

J

Jun Yang

H

Henrik Daub

Z

Zoran Rankovic