Two Flavoenzymes Convert Fungal Polyketide-Nonribosomal Peptide to <i>cis</i> -2-Butene-1,4-dial-Type Carcinogen via Olefin Dihydroxylation and C–C Bond Cleavage
J
Jin-Mei Zhang
(College of Pharmaceutical Sciences)
G
Guan-Yin Yuan
(College of Pharmaceutical Sciences)
M
Min-Xiu Shi
(College of Pharmaceutical Sciences)
Y
Yi Zou
(College of Pharmaceutical Sciences)
Article Details
Volume / Issue
Vol. 147, Issue 43
Published
October 29, 2025
Pages
39310-39320
ISSN
0002-7863
Publisher
American Chemical Society
Journal Info
Journal of the American Chemical Society
American Chemical Society
ISSN: 0002-7863 Physical Sciences
Authors (4)
J
Jin-Mei Zhang
College of Pharmaceutical Sciences
G
Guan-Yin Yuan
College of Pharmaceutical Sciences
M
Min-Xiu Shi
College of Pharmaceutical Sciences
Y
Yi Zou
College of Pharmaceutical Sciences
Related Articles from this Journal
Rational Design of the Composite Perfluoro-Sulfonic Ionomer for High-Performance Proton Exchange Membrane Fuel Cells
Tingting Mao, Haiyang Fan et al.
Jul 2026
10.1021/jacs.6c05625
Ti3+-O Acid–Base Pairs for Efficient Solar-Driven Photothermal Nonoxidative Ethane Dehydrogenation
Yuwen Sun, Kun Gong et al.
Jul 2026
10.1021/jacs.6c08665
Total Synthesis of Benthol A: Evidence for a Structure Revision
Guanghao Huang, Andrea Tomio et al.
Jul 2026
10.1021/jacs.6c05580
Accelerated Self-Photopolymerization of Phenolics in Microdroplets Contributes to the Brown Carbon Formation
Haoran Yu, Xinrui Yang et al.
Jul 2026
10.1021/jacs.6c10186
Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes
Lingxiao Liu, Yang Lu et al.
Jul 2026
10.1021/jacs.6c02874