Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors

Callum Walker; Gabriel Kollarovic; Daniel Weekes; Jennifer Trendell; Ricarda M. Hoffmann; Alexia Martin; Riccardo Ferro; Blanca Navarro-Llinas; Luke Hitchen; Mercedes Pardo Calvo; Nicolae Balan; Harriet Kemp; Alexandra Carroll; Kathryn Davidson; Sarmi Nath; Nadja D’Uonno; Ruifang Lu; Chris Starling; Marieke Otten; Nino Iakobachvili; Chiara Marcozzi; Ilhan Rahman; Jelmar Quist; Lu Yu; Dragomir B. Krastev; Valeria Amodeo; Ioannis Roxanis; Anita Grigoriadis; Richard Bayliss; Jyoti Choudhary; Syed Haider; Jonathon Pines; Stephen J. Pettitt; Christopher J. Lord; Andrew N. J. Tutt

doi:10.1038/s41467-026-69561-3

Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors

C Callum Walker G Gabriel Kollarovic D Daniel Weekes J Jennifer Trendell R Ricarda M. Hoffmann A Alexia Martin R Riccardo Ferro B Blanca Navarro-Llinas L Luke Hitchen M Mercedes Pardo Calvo N Nicolae Balan H Harriet Kemp A Alexandra Carroll K Kathryn Davidson S Sarmi Nath N Nadja D’Uonno R Ruifang Lu C Chris Starling M Marieke Otten N Nino Iakobachvili C Chiara Marcozzi I Ilhan Rahman J Jelmar Quist L Lu Yu D Dragomir B. Krastev V Valeria Amodeo I Ioannis Roxanis A Anita Grigoriadis R Richard Bayliss J Jyoti Choudhary S Syed Haider J Jonathon Pines S Stephen J. Pettitt C Christopher J. Lord A Andrew N. J. Tutt

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published March 11, 2026

DOI 10.1038/s41467-026-69561-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (35)

C

Callum Walker

G

Gabriel Kollarovic

D

Daniel Weekes

J

Jennifer Trendell

R

Ricarda M. Hoffmann

A

Alexia Martin

R

Riccardo Ferro

B

Blanca Navarro-Llinas

L

Luke Hitchen

M

Mercedes Pardo Calvo

N

Nicolae Balan

H

Harriet Kemp

A

Alexandra Carroll

K

Kathryn Davidson

S

Sarmi Nath

N

Nadja D’Uonno

R

Ruifang Lu

C

Chris Starling

M

Marieke Otten

N

Nino Iakobachvili

C

Chiara Marcozzi

I

Ilhan Rahman

J

Jelmar Quist

L

Lu Yu

D

Dragomir B. Krastev

V

Valeria Amodeo

I

Ioannis Roxanis

A

Anita Grigoriadis

R

Richard Bayliss

J

Jyoti Choudhary

S

Syed Haider

J

Jonathon Pines

S

Stephen J. Pettitt

C

Christopher J. Lord

A

Andrew N. J. Tutt

Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors

Article Details

Journal Info

Authors (35)

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