Treatment Response to Mavacamten in Patients With Obstructive Hypertrophic Cardiomyopathy: 96-Week Results From the EXPLORER Cohort of the MAVA–Long-Term Extension Cardiac Magnetic Resonance Imaging Substudy

S Sara Saberi C Christopher M. Kramer (From Baylor University Medical Center, Dallas (M.P.); Imperial College, London (M.P.); RHJ Department of Veterans Affairs, Health System and Medical University of South Carolina, Charleston (M.R.Z., S.E.L.); the Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville (C.M.K.); Flourish Research, Boca Raton, FL (S.J.B.); the Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland (V.M.); the Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China (J.G.); Eli Lilly, Indianapolis (G.J.W., Y.O., M.C.B., K.C.H., M.M.); and the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (B.A.B.).) A Artur Oreziak (National Institute of Cardiology, Warsaw, Poland) A Ahmad Masri (Oregon Health and Science University, Portland) R Roberto Barriales-Villa (Complexo Hospitalario Universitario A Coruña, Instituto de Investigación Biomédica de A Coruña, CIBERCV–Instituto de Salud Carlos III, A Coruña, Spain) T Theodore P. Abraham (University of California San Francisco (T.P.A.).) N Neal K. Lakdawala (Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston) A Andrew Wang L Lubna Choudhury (Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States) F Florian Rader (Cedars-Sinai Medical Center, Los Angeles, CA (F.R.).) O Ofer Havakuk (Tel Aviv Sourasky Medical Center, affiliated to Tel Aviv University, Israel (O.H.).) J John C. Stendahl N Nuno Cardim T Tim Seidler M Mark Sherrid (NYU Langone Health, New York, New York, United States) S Sheila M. Hegde (Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston) R Raymond Y. Kwong M Michael Jerosch-Herold G Ganesh Balaratnam (Bristol Myers Squibb, Princeton, New Jersey, United States) G Gregory Kurio (Bristol Myers Squibb, Princeton, NJ (G.B., G.K.*, S.F.).) S Shawna Fox (Bristol Myers Squibb, Princeton, NJ (G.B., G.K.*, S.F.).) I Iacopo Olivotto (Department of Cardiology, Meyer Children’s Hospital, IRCCS, Florence, Italy) A Anjali Owens

Article Details

Journal Circulation
Volume / Issue Vol. 152, Issue 12
Published September 23, 2025
Pages 905-908
ISSN 0009-7322
Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (23)

S

Sara Saberi

C

Christopher M. Kramer

From Baylor University Medical Center, Dallas (M.P.); Imperial College, London (M.P.); RHJ Department of Veterans Affairs, Health System and Medical University of South Carolina, Charleston (M.R.Z., S.E.L.); the Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville (C.M.K.); Flourish Research, Boca Raton, FL (S.J.B.); the Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland (V.M.); the Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China (J.G.); Eli Lilly, Indianapolis (G.J.W., Y.O., M.C.B., K.C.H., M.M.); and the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (B.A.B.).

A

Artur Oreziak

National Institute of Cardiology, Warsaw, Poland

A

Ahmad Masri

Oregon Health and Science University, Portland

R

Roberto Barriales-Villa

Complexo Hospitalario Universitario A Coruña, Instituto de Investigación Biomédica de A Coruña, CIBERCV–Instituto de Salud Carlos III, A Coruña, Spain

T

Theodore P. Abraham

University of California San Francisco (T.P.A.).

N

Neal K. Lakdawala

Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston

A

Andrew Wang

L

Lubna Choudhury

Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States

F

Florian Rader

Cedars-Sinai Medical Center, Los Angeles, CA (F.R.).

O

Ofer Havakuk

Tel Aviv Sourasky Medical Center, affiliated to Tel Aviv University, Israel (O.H.).

J

John C. Stendahl

N

Nuno Cardim

T

Tim Seidler

M

Mark Sherrid

NYU Langone Health, New York, New York, United States

S

Sheila M. Hegde

Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston

R

Raymond Y. Kwong

M

Michael Jerosch-Herold

G

Ganesh Balaratnam

Bristol Myers Squibb, Princeton, New Jersey, United States

G

Gregory Kurio

Bristol Myers Squibb, Princeton, NJ (G.B., G.K.*, S.F.).

S

Shawna Fox

Bristol Myers Squibb, Princeton, NJ (G.B., G.K.*, S.F.).

I

Iacopo Olivotto

Department of Cardiology, Meyer Children’s Hospital, IRCCS, Florence, Italy

A

Anjali Owens