Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer

S Sara M. Tolaney (Department of Medical Oncology, Dana-Farber Cancer Institute) Z Zefei Jiang (Department of Breast Cancer, Fifth Medical Center of People’s Liberation Army General Hospital, Beijing) Q Qingyuan Zhang (Department of Oncology, Harbin Medical University Cancer Hospital, Harbin, China) R Romualdo Barroso-Sousa (Brasilia Hospital, Rede Américas, Brasilia, Brazil) Y Yeon Hee Park M Mothaffar F. Rimawi (Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston) C Cristina Saura (Vall d’Hebron University Hospital, Barcelona) A Andreas Schneeweiss (National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany) M Masakazu Toi (Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, Tokyo) Y Yee Soo Chae (Department of Oncology and Hematology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, South Korea) Y Yasemin Kemal (Department of Medical Oncology, Faculty of Medicine, Altınbas University, Istanbul, Turkey) M Mukesh Chaudhari (Department of Medical Oncology, HCG Manavata Cancer Center, Mumbai Naka, Nashik, India) M Mehmet A.N. Şendur (Department of Medical Oncology, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara Bilkent City Hospital, Ankara, Turkey) T Toshinari Yamashita (Department of Breast Surgery and Oncology, Kanagawa Cancer Center, Yokohama, Japan) M Monica Casalnuovo (Clinical Oncology Unit, LUCEN, Buenos Aires) M Michael A. Danso (Department of Medical Oncology, Brock Cancer Center, Virginia Oncology Associates, Norfolk) J Jie Liu J Jagdish Shetty (Late Development Oncology, Clinical Development, Oncology Research and Development, AstraZeneca, Gaithersburg, MD) P Pia Herbolsheimer (Late Development Oncology, Clinical Development, Oncology Research and Development, AstraZeneca, Gaithersburg, MD) S Sibylle Loibl (Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany)

Article Details

Volume / Issue Vol. 394, Issue 6
Published February 05, 2026
Pages 551-562
ISSN 0028-4793
Publisher Massachusetts Medical Society

Journal Info

New England Journal of Medicine

Massachusetts Medical Society

ISSN: 0028-4793 Social Sciences

Authors (20)

S

Sara M. Tolaney

Department of Medical Oncology, Dana-Farber Cancer Institute

Z

Zefei Jiang

Department of Breast Cancer, Fifth Medical Center of People’s Liberation Army General Hospital, Beijing

Q

Qingyuan Zhang

Department of Oncology, Harbin Medical University Cancer Hospital, Harbin, China

R

Romualdo Barroso-Sousa

Brasilia Hospital, Rede Américas, Brasilia, Brazil

Y

Yeon Hee Park

M

Mothaffar F. Rimawi

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston

C

Cristina Saura

Vall d’Hebron University Hospital, Barcelona

A

Andreas Schneeweiss

National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany

M

Masakazu Toi

Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, Tokyo

Y

Yee Soo Chae

Department of Oncology and Hematology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, South Korea

Y

Yasemin Kemal

Department of Medical Oncology, Faculty of Medicine, Altınbas University, Istanbul, Turkey

M

Mukesh Chaudhari

Department of Medical Oncology, HCG Manavata Cancer Center, Mumbai Naka, Nashik, India

M

Mehmet A.N. Şendur

Department of Medical Oncology, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara Bilkent City Hospital, Ankara, Turkey

T

Toshinari Yamashita

Department of Breast Surgery and Oncology, Kanagawa Cancer Center, Yokohama, Japan

M

Monica Casalnuovo

Clinical Oncology Unit, LUCEN, Buenos Aires

M

Michael A. Danso

Department of Medical Oncology, Brock Cancer Center, Virginia Oncology Associates, Norfolk

J

Jie Liu

J

Jagdish Shetty

Late Development Oncology, Clinical Development, Oncology Research and Development, AstraZeneca, Gaithersburg, MD

P

Pia Herbolsheimer

Late Development Oncology, Clinical Development, Oncology Research and Development, AstraZeneca, Gaithersburg, MD

S

Sibylle Loibl

Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany