Total Chemical Synthesis of Glucagon Glycoforms Reveals the Remarkable Influence of Natural Glycosylation

Y Yaohao Li (State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica) X Xin Li R Ruihan Wang W Wenqiang Liu (State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica) D Dan Liu Z Zerun Song (State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica) Y Yajing Zhang (State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy) C Chuang Zhang (Key Laboratory of Photochemistry, Beijing National Laboratory for Molecular Sciences, Institute of Chemistry) Z Zhongping Tan (State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica)

Article Details

Volume / Issue Vol. 147, Issue 20
Published May 21, 2025
Pages 17350-17360
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (9)

Y

Yaohao Li

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica

X

Xin Li

R

Ruihan Wang

W

Wenqiang Liu

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica

D

Dan Liu

Z

Zerun Song

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica

Y

Yajing Zhang

State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy

C

Chuang Zhang

Key Laboratory of Photochemistry, Beijing National Laboratory for Molecular Sciences, Institute of Chemistry

Z

Zhongping Tan

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica