Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair

Yang Jiang; Moritz Przybilla; Linda Bakker; Foster C. Jacobs; Dylan Mckeon; Roxanne van der Sluijs; Koichi Sato; Juliëtte Wezenbeek; Joeri van Strien; Jeroen Willems; Alexander E. E. Verkennis; Jamie Barnett; Adrian Baez Ortega; Federico Abascal; Peter W. Villalta; Puck Knipscheer; Iñigo Martincorena; Silvia Balbo; Juan Garaycoechea

doi:10.1038/s41467-025-67072-1

Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair

Y Yang Jiang (Department of Chemistry) M Moritz Przybilla L Linda Bakker F Foster C. Jacobs D Dylan Mckeon R Roxanne van der Sluijs K Koichi Sato J Juliëtte Wezenbeek J Joeri van Strien J Jeroen Willems A Alexander E. E. Verkennis J Jamie Barnett A Adrian Baez Ortega F Federico Abascal P Peter W. Villalta P Puck Knipscheer I Iñigo Martincorena S Silvia Balbo J Juan Garaycoechea

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published December 12, 2025

DOI 10.1038/s41467-025-67072-1

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

Y

Yang Jiang

Department of Chemistry

M

Moritz Przybilla

L

Linda Bakker

F

Foster C. Jacobs

D

Dylan Mckeon

R

Roxanne van der Sluijs

K

Koichi Sato

J

Juliëtte Wezenbeek

J

Joeri van Strien

J

Jeroen Willems

A

Alexander E. E. Verkennis

J

Jamie Barnett

A

Adrian Baez Ortega

F

Federico Abascal

P

Peter W. Villalta

P

Puck Knipscheer

I

Iñigo Martincorena

S

Silvia Balbo

J

Juan Garaycoechea

Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair

Article Details

Journal Info

Authors (19)

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