Time to complete remission is an independent determinant of survival after intensive chemotherapy in AML

R Rithin Nedumannil (1Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia) M Michael Ashby (1Monash University, Australian Centre for Blood Diseases, Melbourne, Australia) J James Rowland (4Department of Haematology, Princess Alexandra Hospital, Brisbane, QLD, Australia) J Jacques A. J. Malherbe (5Department of Haematology, Fiona Stanley Hospital, Murdoch, WA, Australia) J Jared Fairbank (7Department of Haematology, Royal Adelaide Hospital, Central Adelaide Health Network, Adelaide, SA, Australia) K Kelli Gray (1Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia) S Sun Loo (6Alfred Hospital, Melbourne, VIC, Australia) M Matthew Wright (5Department of Haematology, Fiona Stanley Hospital, Murdoch, WA, Australia) J John Reynolds (Clinical Haematology, Alfred Health, Melbourne, VIC, Australia) D Devendra Hiwase (24The Royal Adelaide Hospital, Department of Haematology, Adelaide, Australia) P Paula Marlton (1Princess Alexandra Hospital, Department of Haematology, Brisbane, Australia) S Shaun Fleming A Ashish Bajel (5Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, University of Melbourne, Department of Clinical Haematology, Melbourne, Australia) A Andrew H. Wei

Abstract

Abstract The purpose of this study was to explore and determine the optimal landmark for defining complete remission after intensive induction therapy that best correlates with long-term survival outcome among patients with newly diagnosed acute myeloid leukemia.

Article Details

Journal Blood
Volume / Issue Vol. 146, Issue 13
Published September 25, 2025
Pages 1625-1629
ISSN 0006-4971
Publisher Elsevier BV

Journal Info

Blood

Elsevier BV

ISSN: 0006-4971 Health Sciences

Authors (14)

R

Rithin Nedumannil

1Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia

M

Michael Ashby

1Monash University, Australian Centre for Blood Diseases, Melbourne, Australia

J

James Rowland

4Department of Haematology, Princess Alexandra Hospital, Brisbane, QLD, Australia

J

Jacques A. J. Malherbe

5Department of Haematology, Fiona Stanley Hospital, Murdoch, WA, Australia

J

Jared Fairbank

7Department of Haematology, Royal Adelaide Hospital, Central Adelaide Health Network, Adelaide, SA, Australia

K

Kelli Gray

1Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia

S

Sun Loo

6Alfred Hospital, Melbourne, VIC, Australia

M

Matthew Wright

5Department of Haematology, Fiona Stanley Hospital, Murdoch, WA, Australia

J

John Reynolds

Clinical Haematology, Alfred Health, Melbourne, VIC, Australia

D

Devendra Hiwase

24The Royal Adelaide Hospital, Department of Haematology, Adelaide, Australia

P

Paula Marlton

1Princess Alexandra Hospital, Department of Haematology, Brisbane, Australia

S

Shaun Fleming

A

Ashish Bajel

5Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, University of Melbourne, Department of Clinical Haematology, Melbourne, Australia

A

Andrew H. Wei