The Role of Intrinsically Disordered Domains in Regulating G Protein-Coupled Receptor Signaling

J Jun Xu R Ruoyi Qiu (Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, United States) A Alexander M. Garces (Department of Biophysics) H Harald Hübner (Department of Chemistry and Pharmacy Medicinal Chemistry) X Xinyu Xu (State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)) C Chengyu Hao (Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, United States) D Dorothee Weikert (Department of Chemistry and Pharmacy Medicinal Chemistry) P Peter Gmeiner M Michael T. Lerch (Department of Biophysics) B Brian K. Kobilka

Article Details

Volume / Issue Vol. 148, Issue 1
Published January 14, 2026
Pages 1430-1443
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

J

Jun Xu

R

Ruoyi Qiu

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, United States

A

Alexander M. Garces

Department of Biophysics

H

Harald Hübner

Department of Chemistry and Pharmacy Medicinal Chemistry

X

Xinyu Xu

State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC)

C

Chengyu Hao

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, United States

D

Dorothee Weikert

Department of Chemistry and Pharmacy Medicinal Chemistry

P

Peter Gmeiner

M

Michael T. Lerch

Department of Biophysics

B

Brian K. Kobilka