The impact of elective spine surgery in Canada for degenerative conditions on patient reported health-related quality of life outcomes
Abstract
Abstract The impact of spine surgery on Health-Related Quality-of-Life (HRQoL) outcomes across common spinal degenerative diagnoses is not well characterised. A prospective observational study of patients enrolled in the Canadian Spine Outcomes and Research Network (CSORN) registry was performed. Baseline and 1-year post-operative Short Form-12 Physical Component Summary (PCS) and Mental Component Summary (MCS) scores were collated and compared to normative values from the Canadian General Population (CGP). The percentage of patients achieving the PCS Minimum Clinically Important Difference (MCID) was quantified. 5049 patients were included in the analysis. The mean pre-operative SF-12 PCS was 29.5 and MCS was 44.1. This improved to a mean PCS of 40.5 (p < 0.001) and MCS of 49.3 (p < 0.0001) at 1-year post-operatively. The mean pre-operative PCS was over 2 standard deviations (SD) lower than the normative mean of the CGP; this improved to being close to 1-SD from the normative CGP mean at 1-year post-operatively. Findings were similar across age- and sex-stratified subgroups. Across all conditions, 70–75% of patients achieved the PCS MCID. Fewer patients with cervical myelopathy achieved the PCS MCID (59%). In a surgical cohort, patients with degenerative spinal conditions demonstrate a profound reduction in PCS compared to their peers in the CGP. Spinal surgery was impactful in improving physical function HRQoL outcomes in the majority, but not typically to average population norms.
Article Details
Authors (24)
Ragavan Manoharan
Nisaharan Srikandarajah
Jean-Christophe Murray
Christopher Nielsen
Supriya Singh
Sean Christie
Michael M.H. Yang
Michael Weber
Bernard Larue
Adrienne Kelly
Jerome Paquet
Raphaele Charest-Morin
Guy Hogan
Andrew Glennie
Henry Anh
Eugene Wai
Nicolas Dea
Neil Mason
Kenneth Thomas
Charles Fisher
Hamilton Hall
Christopher Bailey
Mayilee Canizares
Yoga Raja Rampersaud