The H3K27me3 reader UAD-2 recruits a TAF-12-containing transcription machinery to initiate piRNA expression within heterochromatic clusters
X
Xinya Huang
Y
Yan Kuang
M
Meili Li
M
Minjie Hong
D
Demin Xu
J
Jiewei Cheng
T
Tongtong Huang
X
Xianlei Sun
W
Wenkai Wang
Y
Ying Zhou
X
Xuezhu Feng
X
Xiangyang Chen
(Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China)
C
Chengming Zhu
(Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-Sen University)
S
Shouhong Guang
Article Details
Journal
Nature Communications
Volume / Issue
Vol. 16, Issue 1
Published
November 26, 2025
ISSN
2041-1723
Publisher
Nature Portfolio
Authors (14)
X
Xinya Huang
Y
Yan Kuang
M
Meili Li
M
Minjie Hong
D
Demin Xu
J
Jiewei Cheng
T
Tongtong Huang
X
Xianlei Sun
W
Wenkai Wang
Y
Ying Zhou
X
Xuezhu Feng
X
Xiangyang Chen
Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China
C
Chengming Zhu
Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-Sen University
S
Shouhong Guang
Related Articles from this Journal
Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization
Chao Wu, Xu Zhang et al.
Aug 2026
10.1038/s41467-026-76516-1
Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses
Connor Weidle, Natalie Brunette et al.
Aug 2026
10.1038/s41467-026-76114-1
Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk
Ludmila Prokunina-Olsson, Oscar Florez-Vargas et al.
Aug 2026
10.1038/s41467-026-76157-4
Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants
Weiwei Jin, Wen Cao et al.
Aug 2026
10.1038/s41467-026-76470-y
Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain
Bongmin Bae, Katherine Gu et al.
Aug 2026
10.1038/s41467-026-76506-3