TET2-Mutant Clonal Hematopoiesis Promotes Heart Failure With Preserved Ejection Fraction

Ambarish Pandey; Toby Thomas; Yuanyuan Ji; Benjamin Kroger; Peter Carlsgaard; Camila I. Irion; Fatma Kalkan; Matthew Segar; Vinayak Subramanian; Antoni Bayés-Genís; Albert Son; Kira A. Young; Jennifer J. Trowbridge; Naveen Premnath; Nan Jiang; Daniel Daou; Wenhuo Hu; Sarah A. Ware; Dan Tong; Stephen S. Chung

doi:10.1161/circulationaha.124.072909

TET2-Mutant Clonal Hematopoiesis Promotes Heart Failure With Preserved Ejection Fraction

A Ambarish Pandey T Toby Thomas (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) Y Yuanyuan Ji B Benjamin Kroger (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) P Peter Carlsgaard (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) C Camila I. Irion (Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.) F Fatma Kalkan (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) M Matthew Segar (Texas Heart Institute, Houston, Texas, United States) V Vinayak Subramanian (UT Southwestern Medical Center, Dallas, Texas, United States) A Antoni Bayés-Genís A Albert Son (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) K Kira A. Young J Jennifer J. Trowbridge N Naveen Premnath (Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.) N Nan Jiang D Daniel Daou (Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.) W Wenhuo Hu (Department of Pathology, Center of Excellence for Leukemia Studies, St. Jude Children’s Research Hospital, Memphis, TN (W.H.).) S Sarah A. Ware (Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.) D Dan Tong S Stephen S. Chung

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Article Details

Journal Circulation

Volume / Issue Vol. 151, Issue 22

Published June 03, 2025

Pages 1622-1625

DOI 10.1161/circulationaha.124.072909

ISSN 0009-7322

Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (20)

A

Ambarish Pandey

T

Toby Thomas

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

Y

Yuanyuan Ji

B

Benjamin Kroger

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

P

Peter Carlsgaard

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

C

Camila I. Irion

Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.

F

Fatma Kalkan

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

M

Matthew Segar

Texas Heart Institute, Houston, Texas, United States

V

Vinayak Subramanian

UT Southwestern Medical Center, Dallas, Texas, United States

A

Antoni Bayés-Genís

A

Albert Son

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

K

Kira A. Young

J

Jennifer J. Trowbridge

N

Naveen Premnath

Division of Hematology/Oncology, Department of Internal Medicine (T.T., Y.J., B.K., P.C., F.K., A.S., N.P., S.S.C.), UT Southwestern Medical Center, Dallas, TX.

N

Nan Jiang

D

Daniel Daou

Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.

W

Wenhuo Hu

Department of Pathology, Center of Excellence for Leukemia Studies, St. Jude Children’s Research Hospital, Memphis, TN (W.H.).

S

Sarah A. Ware

Division of Cardiology, Department of Internal Medicine (A.P., C.I.I., M.S., V.S., N.J., D.D., S.A.W., D.T.), UT Southwestern Medical Center, Dallas, TX.

D

Dan Tong

S

Stephen S. Chung

TET2-Mutant Clonal Hematopoiesis Promotes Heart Failure With Preserved Ejection Fraction

Article Details

Journal Info

Authors (20)

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