Technical and biological sources of noise confound multiplexed enhancer AAV screening

Avery C. Hunker; John K. Mich; Naz Taskin; Amy Torkelson; Trangthanh Cardenas; Jean-Benoît Lalanne; Joseph T. Mahoney; Darren Bertagnolli; Anish Bhaswanth Chakka; Rushil Chakrabarty; Nicholas P. Donadio; Rebecca Ferrer; Molly Gasperini; Jeff Goldy; Junitta Guzman; Kelly Jin; Shannon Khem; Rana Kutsal; Refugio A. Martinez; Dakota Newman; Nick Pena; Christine Rimorin; Dana Rocha; Nadiya V. Shapovalova; Michael Tieu; Natalie Weed; Thomas Zhou; Rebecca Hodge; Shenqin Yao; Jay Shendure; Kimberly A. Smith; Ed S. Lein; Bosiljka Tasic; Boaz P. Levi; Jonathan T. Ting

doi:10.1038/s41467-026-72147-8

Technical and biological sources of noise confound multiplexed enhancer AAV screening

A Avery C. Hunker J John K. Mich N Naz Taskin A Amy Torkelson T Trangthanh Cardenas J Jean-Benoît Lalanne J Joseph T. Mahoney D Darren Bertagnolli A Anish Bhaswanth Chakka R Rushil Chakrabarty N Nicholas P. Donadio R Rebecca Ferrer M Molly Gasperini J Jeff Goldy J Junitta Guzman K Kelly Jin S Shannon Khem R Rana Kutsal R Refugio A. Martinez D Dakota Newman N Nick Pena C Christine Rimorin D Dana Rocha N Nadiya V. Shapovalova M Michael Tieu N Natalie Weed T Thomas Zhou R Rebecca Hodge S Shenqin Yao J Jay Shendure K Kimberly A. Smith E Ed S. Lein B Bosiljka Tasic B Boaz P. Levi J Jonathan T. Ting

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published April 28, 2026

DOI 10.1038/s41467-026-72147-8

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (35)

A

Avery C. Hunker

J

John K. Mich

N

Naz Taskin

A

Amy Torkelson

T

Trangthanh Cardenas

J

Jean-Benoît Lalanne

J

Joseph T. Mahoney

D

Darren Bertagnolli

A

Anish Bhaswanth Chakka

R

Rushil Chakrabarty

N

Nicholas P. Donadio

R

Rebecca Ferrer

M

Molly Gasperini

J

Jeff Goldy

J

Junitta Guzman

K

Kelly Jin

S

Shannon Khem

R

Rana Kutsal

R

Refugio A. Martinez

D

Dakota Newman

N

Nick Pena

C

Christine Rimorin

D

Dana Rocha

N

Nadiya V. Shapovalova

M

Michael Tieu

N

Natalie Weed

T

Thomas Zhou

R

Rebecca Hodge

S

Shenqin Yao

J

Jay Shendure

K

Kimberly A. Smith

E

Ed S. Lein

B

Bosiljka Tasic

B

Boaz P. Levi

J

Jonathan T. Ting

Technical and biological sources of noise confound multiplexed enhancer AAV screening

Article Details

Journal Info

Authors (35)

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