Targeting tRNA-dependent tyrosine usage unveils a metabolic vulnerability in hepatocellular carcinoma

H Hongli Zhang Z Zixuan Wang Y Yiqi Zhao X Xiya Deng J Jian Zhang F Fei Shang (Department of Physics) H Hongjie Zhang (State Key Laboratory of Rare Earths) Y Yan Liu H Hongbo Wang (State Key Laboratory of High Pressure and Superhard Materials, College of Physics) Y Yating Yang H Huiyu Lin B Bo Zhang C Ce Liu (State Key Laboratory of Quantum Functional Materials and Department of Chemistry) F Fan Guo (Research Center for Industries of the Future) R Ruolin Zhang Q Qipeng Yuan Y Yue Feng S Shi-Zhong Luo (State Key Laboratory of Green Biomanufacturing, College of Life Science and Technology, Beijing University of Chemical Technology) W Wei-Dong Chen Y Yan-Dong Wang

Article Details

Volume / Issue Vol. 17, Issue 1
Published March 06, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

H

Hongli Zhang

Z

Zixuan Wang

Y

Yiqi Zhao

X

Xiya Deng

J

Jian Zhang

F

Fei Shang

Department of Physics

H

Hongjie Zhang

State Key Laboratory of Rare Earths

Y

Yan Liu

H

Hongbo Wang

State Key Laboratory of High Pressure and Superhard Materials, College of Physics

Y

Yating Yang

H

Huiyu Lin

B

Bo Zhang

C

Ce Liu

State Key Laboratory of Quantum Functional Materials and Department of Chemistry

F

Fan Guo

Research Center for Industries of the Future

R

Ruolin Zhang

Q

Qipeng Yuan

Y

Yue Feng

S

Shi-Zhong Luo

State Key Laboratory of Green Biomanufacturing, College of Life Science and Technology, Beijing University of Chemical Technology

W

Wei-Dong Chen

Y

Yan-Dong Wang