Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol

Q Qiguang Wang X Xue Xia (Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University) H Huan Zhang (School of Agriculture and Biology) Y Yue Li L Lei Zhu Y Yulong Shi Y Yuzhao Tang J Jian Cheng (State Key Laboratory of Precision and Intelligent Chemistry, Department of Polymer Science and Engineering, School of Chemistry and Materials Science) X Xuhui Hui H Huile Gao (Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University)

Article Details

Volume / Issue Vol. 16, Issue 1
Published July 10, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (10)

Q

Qiguang Wang

X

Xue Xia

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University

H

Huan Zhang

School of Agriculture and Biology

Y

Yue Li

L

Lei Zhu

Y

Yulong Shi

Y

Yuzhao Tang

J

Jian Cheng

State Key Laboratory of Precision and Intelligent Chemistry, Department of Polymer Science and Engineering, School of Chemistry and Materials Science

X

Xuhui Hui

H

Huile Gao

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University