Targeted degradation of endogenous YAP by nanobody bioPROTAC inhibits tumor progression

R Runhua Zhou H Huifang Wang G Gui-Ming Zhang Y Yawei Liu (Beijing Key Laboratory of Solid State Battery and Energy Storage Process, State Key Laboratory of Mesoscience and Engineering, Institute of Process Engineering) X Xiao-Lian Liu Z Zhifen Li G Guangwei Shi J Junling Yuan C Chengming Qu Y Yang Li L Liang Chen J Jingnan Huang H Hongchao Zhou L Lingyun Dai C Chongzhi Bai J Jigang Wang (Artemisinin Research Center and Institute of Chinese Materia Medica) L Le Yu (Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science) Z Zhijie Li (Molecular Medicine Program, The Hospital for Sick Children) Y Yi-lei Li

Article Details

Volume / Issue Vol. 16, Issue 1
Published October 23, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

R

Runhua Zhou

H

Huifang Wang

G

Gui-Ming Zhang

Y

Yawei Liu

Beijing Key Laboratory of Solid State Battery and Energy Storage Process, State Key Laboratory of Mesoscience and Engineering, Institute of Process Engineering

X

Xiao-Lian Liu

Z

Zhifen Li

G

Guangwei Shi

J

Junling Yuan

C

Chengming Qu

Y

Yang Li

L

Liang Chen

J

Jingnan Huang

H

Hongchao Zhou

L

Lingyun Dai

C

Chongzhi Bai

J

Jigang Wang

Artemisinin Research Center and Institute of Chinese Materia Medica

L

Le Yu

Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science

Z

Zhijie Li

Molecular Medicine Program, The Hospital for Sick Children

Y

Yi-lei Li