Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS

Z Zhehui Hu (State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology) Z Zhiyong Yin (Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany) G Guihu Lu (State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology) Q Qi Luo (Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine) X Xiyuan He (State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology) L Liming Zhan (State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology) B Bernd Goldfuss (Institute of Organic Chemistry, Department of Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany) J Juan Xu (Shanghai Engineering Research Center of Biotransformation of Organic Solid Waste, School of Ecological and Environmental Sciences) G Guangkai Bian (State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology) J Jeroen S. Dickschat (Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany)

Article Details

Volume / Issue Vol. 148, Issue 11
Published March 25, 2026
Pages 12377-12386
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

Z

Zhehui Hu

State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology

Z

Zhiyong Yin

Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany

G

Guihu Lu

State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology

Q

Qi Luo

Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine

X

Xiyuan He

State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology

L

Liming Zhan

State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology

B

Bernd Goldfuss

Institute of Organic Chemistry, Department of Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany

J

Juan Xu

Shanghai Engineering Research Center of Biotransformation of Organic Solid Waste, School of Ecological and Environmental Sciences

G

Guangkai Bian

State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology

J

Jeroen S. Dickschat

Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany