Synaptotagmin-1 serves as a primary Zn2+ sensor to mediate spontaneous neurotransmitter release under pathological conditions

Y Yijuan Xiang L Lele Cui J Jingyu Yao (Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University) X Xiaochu Lou M Mengdan Wu J Jingxiao Huo (Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University) J Jiaqi Fan H Hao Li K KaiYu Li X Xiaodong Wang (CAS Key Laboratory of Science and Technology on Applied Catalysis) Y Yeon-kyun Shin X Xiaofei Yang C Changhe Wang (Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University) Y Ying Lai

Article Details

Volume / Issue Vol. 16, Issue 1
Published August 02, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

Y

Yijuan Xiang

L

Lele Cui

J

Jingyu Yao

Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University

X

Xiaochu Lou

M

Mengdan Wu

J

Jingxiao Huo

Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University

J

Jiaqi Fan

H

Hao Li

K

KaiYu Li

X

Xiaodong Wang

CAS Key Laboratory of Science and Technology on Applied Catalysis

Y

Yeon-kyun Shin

X

Xiaofei Yang

C

Changhe Wang

Department of Neurology, the Second Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University

Y

Ying Lai