Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma

Bartimée Galvan; Loïc Ongena; Jonathan Bruyr; Gregory Fettweis; Eva Lucarelli; Arnaud Lavergne; Emeline Mariavelle; Tina M. O’Grady; Zahrat El Oula Hassoun; Margaux Claes; Laurence Dubois; Kevin A. W. Lee; Véronique Kruys; Cyril Gueydan; Jules Durand; Eric Hervouet; Florian H. Geyer; Ana Banito; Roland Imle; Lianghao Mao; Ashok K. Jayavelu; Thomas G. P. Grünewald; Florencia Cidre-Aranaz; Jean-Claude Twizere; Franck Dequiedt

doi:10.1038/s41467-025-61725-x

Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma

B Bartimée Galvan L Loïc Ongena J Jonathan Bruyr G Gregory Fettweis E Eva Lucarelli A Arnaud Lavergne E Emeline Mariavelle T Tina M. O’Grady (Tempus AI, Inc.) Z Zahrat El Oula Hassoun M Margaux Claes L Laurence Dubois K Kevin A. W. Lee V Véronique Kruys C Cyril Gueydan J Jules Durand E Eric Hervouet F Florian H. Geyer A Ana Banito R Roland Imle L Lianghao Mao A Ashok K. Jayavelu T Thomas G. P. Grünewald F Florencia Cidre-Aranaz J Jean-Claude Twizere F Franck Dequiedt

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published July 16, 2025

DOI 10.1038/s41467-025-61725-x

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (25)

B

Bartimée Galvan

L

Loïc Ongena

J

Jonathan Bruyr

G

Gregory Fettweis

E

Eva Lucarelli

A

Arnaud Lavergne

E

Emeline Mariavelle

T

Tina M. O’Grady

Tempus AI, Inc.

Z

Zahrat El Oula Hassoun

M

Margaux Claes

L

Laurence Dubois

K

Kevin A. W. Lee

V

Véronique Kruys

C

Cyril Gueydan

J

Jules Durand

E

Eric Hervouet

F

Florian H. Geyer

A

Ana Banito

R

Roland Imle

L

Lianghao Mao

A

Ashok K. Jayavelu

T

Thomas G. P. Grünewald

F

Florencia Cidre-Aranaz

J

Jean-Claude Twizere

F

Franck Dequiedt

Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma

Article Details

Journal Info

Authors (25)

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