Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

Emily Puumala; Meganathan Nandakumar; Bonnie Yiu; Peter J. Stogios; Benjamin G. Strickland; Robert Zarnowski; Xiaoyu Wang; Noelle S. Williams; Alexei Savchenko; David R. Andes; Nicole Robbins; Luke Whitesell; Timothy M. Willson; Leah E. Cowen

doi:10.1038/s41467-025-57346-z

Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

E Emily Puumala M Meganathan Nandakumar B Bonnie Yiu P Peter J. Stogios B Benjamin G. Strickland R Robert Zarnowski (Department of Medicine, University of Wisconsin-Madison) X Xiaoyu Wang N Noelle S. Williams (Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, United States) A Alexei Savchenko D David R. Andes N Nicole Robbins L Luke Whitesell T Timothy M. Willson L Leah E. Cowen

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published March 04, 2025

DOI 10.1038/s41467-025-57346-z

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

E

Emily Puumala

M

Meganathan Nandakumar

B

Bonnie Yiu

P

Peter J. Stogios

B

Benjamin G. Strickland

R

Robert Zarnowski

Department of Medicine, University of Wisconsin-Madison

X

Xiaoyu Wang

N

Noelle S. Williams

Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, United States

A

Alexei Savchenko

D

David R. Andes

N

Nicole Robbins

L

Luke Whitesell

T

Timothy M. Willson

L

Leah E. Cowen

Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

Article Details

Journal Info

Authors (14)

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