Journal of the American Chemical Society

Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch

C Chungen Li X Xueyi Yang (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States) K Kyle A. Dickerson (Department of Molecular, Cellular and Developmental Biology) P Patrick R. A. Zanon (The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States) N Noah A. Springer (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States) J Jielei Wang (The Scripps Research Institute, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States) Y Yilin Jia (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States) N Nikhil C. Munshi R Robert T. Batey (Department of Molecular, Cellular and Developmental Biology) M Matthew D. Disney (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States)
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Article Details

Volume / Issue Vol. 147, Issue 42
Published October 22, 2025
Pages 38684-38690
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (10)

C

Chungen Li

X

Xueyi Yang

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

K

Kyle A. Dickerson

Department of Molecular, Cellular and Developmental Biology

P

Patrick R. A. Zanon

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States

N

Noah A. Springer

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

J

Jielei Wang

The Scripps Research Institute, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States

Y

Yilin Jia

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

N

Nikhil C. Munshi

R

Robert T. Batey

Department of Molecular, Cellular and Developmental Biology

M

Matthew D. Disney

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

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