Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide

Guangning Chen; Jingjing Shen; Xinyu Li; Menghui Sun; Sheng Dong; Ying Sun; Achiraya Khamleng; Xuanwei Mei; Yuying Zhang; Guanchen Liu; Fangyi Chen; Xiao Song; Kaimeng Liu; Yingang Feng; Changhu Xue; Yaoguang Chang

doi:10.1038/s41467-025-63891-4

Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide

G Guangning Chen J Jingjing Shen X Xinyu Li (Cell and Molecular Biology Program) M Menghui Sun S Sheng Dong Y Ying Sun A Achiraya Khamleng X Xuanwei Mei Y Yuying Zhang (School of Medicine) G Guanchen Liu F Fangyi Chen X Xiao Song K Kaimeng Liu Y Yingang Feng (State Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Key Laboratory of Shandong Energy Biological Genetic Resources, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences) C Changhu Xue Y Yaoguang Chang

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published October 17, 2025

DOI 10.1038/s41467-025-63891-4

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

G

Guangning Chen

J

Jingjing Shen

X

Xinyu Li

Cell and Molecular Biology Program

M

Menghui Sun

S

Sheng Dong

Y

Ying Sun

A

Achiraya Khamleng

X

Xuanwei Mei

Y

Yuying Zhang

School of Medicine

G

Guanchen Liu

F

Fangyi Chen

X

Xiao Song

K

Kaimeng Liu

Y

Yingang Feng

State Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Key Laboratory of Shandong Energy Biological Genetic Resources, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences

C

Changhu Xue

Y

Yaoguang Chang

Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide

Article Details

Journal Info

Authors (16)

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