Structure–activity relationship studies of febuxostat derivatives identify potent anti-lung cancer agents that induce DNA damage and autophagy

Xixi Hou; Xuanwei Zhang; Jingjing Guo; Yajie Guo; Jianxue Yang

doi:10.1038/s41598-026-60785-3

Structure–activity relationship studies of febuxostat derivatives identify potent anti-lung cancer agents that induce DNA damage and autophagy

X Xixi Hou X Xuanwei Zhang J Jingjing Guo (Center for Clinical Research and Translational Medicine, Yangpu Hospital, School of Medicine, Tongji University) Y Yajie Guo J Jianxue Yang

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 16, Issue 1

Published July 21, 2026

DOI 10.1038/s41598-026-60785-3

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (5)

X

Xixi Hou

X

Xuanwei Zhang

J

Jingjing Guo

Center for Clinical Research and Translational Medicine, Yangpu Hospital, School of Medicine, Tongji University

Y

Yajie Guo

J

Jianxue Yang

Structure–activity relationship studies of febuxostat derivatives identify potent anti-lung cancer agents that induce DNA damage and autophagy

Article Details

Journal Info

Authors (5)

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