Nature Communications

Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitination

X Xiangwei Wu H Huasong Ai (School of Pharmaceutical Sciences, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, Center for Chemical Glycobiology-Zhangjiang Institute for Advanced Study, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, Research Center for Chemical Biology of Post-translational Modifications) J Junxiong Mao H Hongyi Cai (Clinical Mass Spectrometry Core, National Institute of Diabetes and Digestive and Kidney Diseases, NIH) L Lu-Jun Liang (Center for Bioanalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale) Z Zebin Tong (Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry) Z Zhiheng Deng (Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry) Q Qingyun Zheng (School of Pharmaceutical Science, Institute of Translational Medicine, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target) L Lei Liu M Man Pan
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Article Details

Volume / Issue Vol. 16, Issue 1
Published May 09, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio
ISSN: 2041-1723 Open Access Life Sciences

Authors (10)

X

Xiangwei Wu

H

Huasong Ai

School of Pharmaceutical Sciences, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, Center for Chemical Glycobiology-Zhangjiang Institute for Advanced Study, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, Research Center for Chemical Biology of Post-translational Modifications

J

Junxiong Mao

H

Hongyi Cai

Clinical Mass Spectrometry Core, National Institute of Diabetes and Digestive and Kidney Diseases, NIH

L

Lu-Jun Liang

Center for Bioanalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale

Z

Zebin Tong

Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry

Z

Zhiheng Deng

Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry

Q

Qingyun Zheng

School of Pharmaceutical Science, Institute of Translational Medicine, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target

L

Lei Liu

M

Man Pan

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