Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices

T Thomas M. DeAngelo U Utsarga Adhikary K Kyle J. Korshavn H Hyuk-Soo Seo (Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School) C Clara R. Brotzen-Smith C Christina M. Camara S Sirano Dhe-Paganon (Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School) G Gregory H. Bird T Thomas E. Wales L Loren D. Walensky (Department of Pediatric Oncology, Dana–Farber Cancer Institute, Boston)

Article Details

Volume / Issue Vol. 16, Issue 1
Published September 29, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (10)

T

Thomas M. DeAngelo

U

Utsarga Adhikary

K

Kyle J. Korshavn

H

Hyuk-Soo Seo

Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School

C

Clara R. Brotzen-Smith

C

Christina M. Camara

S

Sirano Dhe-Paganon

Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School

G

Gregory H. Bird

T

Thomas E. Wales

L

Loren D. Walensky

Department of Pediatric Oncology, Dana–Farber Cancer Institute, Boston