Structural Heterogeneity of Proteoform-Ligand Complexes in Adenosine Monophosphate-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry

Hsin-Ju Chan

Department of Chemistry

Boris Krichel

Department of Cell and Regenerative Biology

Liam J. Bandura

Department of Chemistry

Emily A. Chapman

Department of Chemistry

Holden T. Rogers

Department of Chemistry

Matthew S. Fischer

Department of Chemistry

David S. Roberts

Zhan Gao

School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Functional Biomaterials Engineering Technology Research Center

Man-Di Wang

Department of Chemistry

Jingshing Wu

Department of Pediatrics, Cardiovascular Research Center

Charlotte Uetrecht

School of Life Sciences

Song Jin

Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), Department of Applied Chemistry

Ying Ge