Structural Basis for Medium-Chain Dehydrogenase/Reductase-Catalyzed Reductive Cyclization in Polycyclic Tetramate Macrolactam Biosynthesis

Xiangqian Xie

State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center of Nanjing University, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering

Fan Li

Yanxin Mu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine

Mengyao Lu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine

Jie Luo

Haoxin Wang

State Key Laboratory of Microbial Technology

Yuemao Shen

Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences

Liangcheng Du

Department of Chemistry

Deyu Zhu

School of Basic Medical Sciences

Yaoyao Li