Structural and Mechanistic Basis for Orthoester Formation by αKG-Free Endoperoxide Isomerase in Novofumigatonin Biosynthesis

Y Yi Yang X Xuan Zhang T Takahiro Mori (Graduate School of Pharmaceutical Sciences) Z Zhiyang Quan (RIKEN Center for Sustainable Resource Science) T Takayoshi Awakawa (RIKEN Center for Sustainable Resource Science) Y Yiling Ding (Graduate School of Pharmaceutical Sciences) B Binju Wang (State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering) I Ikuro Abe

Article Details

Volume / Issue Vol. 147, Issue 50
Published December 17, 2025
Pages 46085-46093
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (8)

Y

Yi Yang

X

Xuan Zhang

T

Takahiro Mori

Graduate School of Pharmaceutical Sciences

Z

Zhiyang Quan

RIKEN Center for Sustainable Resource Science

T

Takayoshi Awakawa

RIKEN Center for Sustainable Resource Science

Y

Yiling Ding

Graduate School of Pharmaceutical Sciences

B

Binju Wang

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering

I

Ikuro Abe