Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors

Jianjun Cao; Matthew J. Belousoff; Rachel M. Johnson; Peter Keov; Zamara Mariam; Giuseppe Deganutti; George Christopoulos; Caroline A. Hick; Steffen Reedtz-Runge; Tine Glendorf; Borja Ballarín-González; Kirsten Raun; Charles Bayly-Jones; Denise Wootten; Patrick M. Sexton

doi:10.1038/s41467-025-58680-y

Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors

J Jianjun Cao M Matthew J. Belousoff R Rachel M. Johnson P Peter Keov Z Zamara Mariam (Centre for Health and Life Sciences, Coventry University) G Giuseppe Deganutti G George Christopoulos (Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University) C Caroline A. Hick S Steffen Reedtz-Runge T Tine Glendorf B Borja Ballarín-González K Kirsten Raun C Charles Bayly-Jones D Denise Wootten P Patrick M. Sexton

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published April 10, 2025

DOI 10.1038/s41467-025-58680-y

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (15)

J

Jianjun Cao

M

Matthew J. Belousoff

R

Rachel M. Johnson

P

Peter Keov

Z

Zamara Mariam

Centre for Health and Life Sciences, Coventry University

G

Giuseppe Deganutti

G

George Christopoulos

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University

C

Caroline A. Hick

S

Steffen Reedtz-Runge

T

Tine Glendorf

B

Borja Ballarín-González

K

Kirsten Raun

C

Charles Bayly-Jones

D

Denise Wootten

P

Patrick M. Sexton

Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors

Article Details

Journal Info

Authors (15)

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