Stability and Degradation-based Proteome Profiling Reveals Cannabidiol as a Promising CDC123-eIF2γ Inhibitor for Colorectal Cancer Therapy

H Hengyuan Yu (College of Pharmaceutical Sciences) Y Yang Chen M Mingfei Wu (School of Pharmacy) W Wentao Wang (College of Pharmaceutical Sciences) J Junjie Qiu R Rui Xu (College & Hospital of Stomatology) J Jie Tong (PET Center, Department of Radiology and Biomedical Imaging) Y Yong Chen X Xuesong Liu (College of Pharmaceutical Sciences) Y Yongjiang Wu (College of Pharmaceutical Sciences) P Pengfei Xu T Tao Hu J Jing Miao (Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences) X Xiaowu Dong (College of Pharmaceutical Sciences) J Jinxin Che (College of Pharmaceutical Sciences) S Shuai Liu (College of Materials Science and Engineering) S Su Zeng (College of Pharmaceutical Sciences) T Tengfei Xu (Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences)

Article Details

Volume / Issue Vol. 148, Issue 3
Published January 28, 2026
Pages 3712-3722
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (18)

H

Hengyuan Yu

College of Pharmaceutical Sciences

Y

Yang Chen

M

Mingfei Wu

School of Pharmacy

W

Wentao Wang

College of Pharmaceutical Sciences

J

Junjie Qiu

R

Rui Xu

College & Hospital of Stomatology

J

Jie Tong

PET Center, Department of Radiology and Biomedical Imaging

Y

Yong Chen

X

Xuesong Liu

College of Pharmaceutical Sciences

Y

Yongjiang Wu

College of Pharmaceutical Sciences

P

Pengfei Xu

T

Tao Hu

J

Jing Miao

Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences

X

Xiaowu Dong

College of Pharmaceutical Sciences

J

Jinxin Che

College of Pharmaceutical Sciences

S

Shuai Liu

College of Materials Science and Engineering

S

Su Zeng

College of Pharmaceutical Sciences

T

Tengfei Xu

Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences