Spatiotemporal aggregation and population distribution characteristics of HIV/AIDS in Nanchang city: A monitoring analysis from 2012–2021

L Li Wang (The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital Zhengzhou China) L Liang Lu Z Zhibin Tu L Liping Qiu (Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province) X Xiaoqin Tong J Jinyi Sun (Department of Molecular Microbiology, Washington University, School of Medicine) R Rui Liu

Abstract

AIDS is a major public health issue. As a transportation and economic hub in central China, Nanchang has frequent population mobility and unbalanced regional development, making it urgent to explore the prevalence characteristics of HIV/AIDS. Based on HIV/AIDS surveillance data in Nanchang from 2012 to 2021, this study innovatively integrates the Joinpoint regression model with spatiotemporal geographic information technology to construct an epidemiological analysis framework of “time-space-population”. The results show that a total of 3,789 HIV/AIDS infection cases were reported in the decade, with the growth rate of new cases (5.4%) significantly higher than the population growth rate (2.1%). There is a negative correlation between incidence and mortality, and men and the elderly (≥65 years old) are at prominent infection risk. Spatially, cases show significant heterogeneity, with “high-high” clustering areas concentrated in the city center and gradually expanding to surrounding areas, which is related to factors such as population density. The study provides a scientific basis for targeted interventions for men and the elderly, optimization of prevention and control strategies, and regional collaboration.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 21, Issue 2
Published February 05, 2026
Pages e0342375
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (7)

L

Li Wang

The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital Zhengzhou China

L

Liang Lu

Z

Zhibin Tu

L

Liping Qiu

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province

X

Xiaoqin Tong

J

Jinyi Sun

Department of Molecular Microbiology, Washington University, School of Medicine

R

Rui Liu