Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids

Francesca Fagiani; Edoardo Pedrini; Maria Sofia Martire; Gaia Gastoldi; Colin Vanden Bulcke; Jing-Ping Lin; Dragan Maric; Elena Brambilla; Francesca Ruffini; Carolina Peri; Peter A. Calabresi; Pietro Maggi; Paola Panina-Bordignon; Gianvito Martino; Daniel S. Reich; Martina Absinta

doi:10.1038/s41467-025-63371-9

Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids

F Francesca Fagiani E Edoardo Pedrini M Maria Sofia Martire G Gaia Gastoldi C Colin Vanden Bulcke J Jing-Ping Lin D Dragan Maric E Elena Brambilla F Francesca Ruffini C Carolina Peri P Peter A. Calabresi (Department of Neurology, Johns Hopkins University School of Medicine, Baltimore) P Pietro Maggi P Paola Panina-Bordignon G Gianvito Martino D Daniel S. Reich M Martina Absinta

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published September 26, 2025

DOI 10.1038/s41467-025-63371-9

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

F

Francesca Fagiani

E

Edoardo Pedrini

M

Maria Sofia Martire

G

Gaia Gastoldi

C

Colin Vanden Bulcke

J

Jing-Ping Lin

D

Dragan Maric

E

Elena Brambilla

F

Francesca Ruffini

C

Carolina Peri

P

Peter A. Calabresi

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore

P

Pietro Maggi

P

Paola Panina-Bordignon

G

Gianvito Martino

D

Daniel S. Reich

M

Martina Absinta

Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids

Article Details

Journal Info

Authors (16)

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