SPA-PNN ligand for the kinetic resolution of carbocyclic and heterocyclic spiranes by asymmetric hydrogenation

Y Yong-Yao Li K Ka Lu (School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence) J Ju-Song Yang (School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence) X Xiao-Ming Zhang (State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering) F Fu-Min Zhang (State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering) Y Yong-Qiang Tu (State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering)

Article Details

Volume / Issue Vol. 16, Issue 1
Published July 02, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (6)

Y

Yong-Yao Li

K

Ka Lu

School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence

J

Ju-Song Yang

School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence

X

Xiao-Ming Zhang

State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering

F

Fu-Min Zhang

State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering

Y

Yong-Qiang Tu

State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering