SlPLT6 controls ripening initiation and quality traits through modulation of histone acetylation and methylation in tomato

X Xiaoqing He (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) Y Yi Wu P Peng Shu (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) Y Yanpeng Yin (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) H Heng Deng (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) S Shiyu Ying (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) M Mengbo Wu P Panpan Zhao (State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry) T Tengbo Huang (Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University) J Julien Pirrello (Laboratoire de Recherche en Sciences Végétales–Génomique et Biotechnologie des Fruits-UMR5546, Université de Toulouse, CNRS, Université Paul Sabatier, Institut Polytechnique de Toulouse, Auzeville) Y Yang Zhang D Don Grierson (School of Biosciences, University of Nottingham, Sutton Bonington Campus) Z Zhenhui Zhong (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University) Y Yiguo Hong M Mondher Bouzayen (Laboratoire de Recherche en Sciences Végétales–Génomique et Biotechnologie des Fruits-UMR5546, Université de Toulouse, CNRS, Université Paul Sabatier, Institut Polytechnique de Toulouse, Auzeville) M Mingchun Liu (Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University)

Abstract

Improving fruit growth and quality without compromising yield is a highly sought-after goal in crop breeding. Here, we report that an EAR motif-containing transcription factor SlPLT6 controls the onset of fruit ripening and quality traits in tomato. SlPLT6 knockout caused precocious ripening initiation and enhanced fruit qualities without penalizing yield in two tomato cultivars. SlPLT6 represses genes involved in ripening initiation and major quality traits by directly binding to their promoters. Moreover, SlPLT6 connects two repressive mechanisms by recruiting Histone Deacetylase 1 via its C-terminal EAR motif and LIKE HETEROCHROMATIN PROTEIN 1b through the first AP2 domain. Furthermore, Sly-miR159 acts upstream of SlPLT6 to release its repression. Taken together, our data provide insights into the operating mode of SlPLT6 in modulating fruit ripening and quality traits and define a unique gene for targeted crop improvement aimed at upgrading fruit quality without yield penalty.

Article Details

Volume / Issue Vol. 122, Issue 24
Published June 17, 2025
ISSN 0027-8424
Publisher National Academy of Sciences

Authors (16)

X

Xiaoqing He

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

Y

Yi Wu

P

Peng Shu

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

Y

Yanpeng Yin

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

H

Heng Deng

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

S

Shiyu Ying

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

M

Mengbo Wu

P

Panpan Zhao

State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry

T

Tengbo Huang

Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University

J

Julien Pirrello

Laboratoire de Recherche en Sciences Végétales–Génomique et Biotechnologie des Fruits-UMR5546, Université de Toulouse, CNRS, Université Paul Sabatier, Institut Polytechnique de Toulouse, Auzeville

Y

Yang Zhang

D

Don Grierson

School of Biosciences, University of Nottingham, Sutton Bonington Campus

Z

Zhenhui Zhong

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University

Y

Yiguo Hong

M

Mondher Bouzayen

Laboratoire de Recherche en Sciences Végétales–Génomique et Biotechnologie des Fruits-UMR5546, Université de Toulouse, CNRS, Université Paul Sabatier, Institut Polytechnique de Toulouse, Auzeville

M

Mingchun Liu

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University