Site-Specific Chemoselective Cyclization and Fluorogenic Modification of Protein Cysteine Residues: From Side-Chain to Backbone

H Hui Zhang (The Fourth Hospital of Hebei Medical University Shijiazhuang China) K Ke Wei (The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China) W Wanyi Yu (The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China) Y Youshen Wu (MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China) X Xuhong Qian (State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China) E Eric V. Anslyn (Department of Chemistry) X Xiaolong Sun (The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China)

Article Details

Volume / Issue Vol. 147, Issue 36
Published September 10, 2025
Pages 32818-32829
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (7)

H

Hui Zhang

The Fourth Hospital of Hebei Medical University Shijiazhuang China

K

Ke Wei

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China

W

Wanyi Yu

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China

Y

Youshen Wu

MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China

X

Xuhong Qian

State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China

E

Eric V. Anslyn

Department of Chemistry

X

Xiaolong Sun

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, No. 28 West Xianning Road, Xi’an 710049, People’s Republic of China