Single‐Site Nickel‐Anchored Photosensitive Covalent Organic Framework for Metallaphotocatalytic C─S/C─N Cross‐Coupling Reactions

Y Yang‐Yang Xiong (GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China) S Songlin Deng (GBRCE for Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry) H Haiping Wang (State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences) S Shi‐Hua Liu (GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China) P Peter VanNatta (Department of Chemistry) J Jie‐Li Lin (GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China) J Juejing Liu (Department of Chemistry, Washington State University) C Chengjun Sun (Advanced Photon Source) X Xiaofeng Guo (Department of Chemistry, Washington State University) C Cheng‐Xia Chen (GBRCE For Functional Molecular Engineering Lehn Institute of Functional Materials IGCME School of Chemistry Sun Yat‐Sen University Guangzhou P. R. China) A Ayman Nafady (Department of Chemistry, College of Science) A Abdullah M. Al‐Enizi (Department of Chemistry, College of Science King Saud University Riyadh Saudi Arabia) S Shengqian Ma (Department of Chemistry)

Abstract

ABSTRACT The development of multifunctionally heterogeneous catalysts, simultaneously bearing photosensitizer and nonnoble metal catalyst in close spatial proximity, represents a promising solution for promoting metallaphotoredox‐mediated catalysis, albeit it remains challenging. Herein, a single‐site Ni‐functionalized photosensitive covalent organic framework (COF), TTA‐BPyDA(Ni)‐COF, has been constructed by implementing a postsynthetic metallization strategy in a triazine‐based COF scaffold. The precise integration of photosensitizer and Ni‐catalytic active centers within TTA‐BPyDA(Ni)‐COF not only dramatically improves the metallaphotocatalytic (MPC) performance in C─S/C─N cross‐coupling reaction between diverse thiols/amines and aryl iodides with electron‐rich/neutral/deficient groups but also confers TTA‐BPyDA(Ni)‐COF with outstanding recyclability and durability compared with its homogeneous counterpart. Importantly, the MPC C─S/C─N reaction mechanisms have been well established by comprehensive experimental and theoretical simulations. This work offers valuable insights for developing single‐site nonnoble metal‐functionalized COF catalytic platforms that integrate photoredox centers with catalytic transition‐metal cores.

Article Details

Volume / Issue Vol. 65, Issue 21
Published May 18, 2026
ISSN 1433-7851
Publisher Wiley

Journal Info

Angewandte Chemie International Edition

Wiley

ISSN: 1433-7851 Physical Sciences

Authors (13)

Y

Yang‐Yang Xiong

GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China

S

Songlin Deng

GBRCE for Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry

H

Haiping Wang

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences

S

Shi‐Hua Liu

GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China

P

Peter VanNatta

Department of Chemistry

J

Jie‐Li Lin

GBRCE For Functional Molecular Engineering, Lehn Institute of Functional Materials, IGCME, School of Chemistry Sun Yat‐Sen University Guangzhou China

J

Juejing Liu

Department of Chemistry, Washington State University

C

Chengjun Sun

Advanced Photon Source

X

Xiaofeng Guo

Department of Chemistry, Washington State University

C

Cheng‐Xia Chen

GBRCE For Functional Molecular Engineering Lehn Institute of Functional Materials IGCME School of Chemistry Sun Yat‐Sen University Guangzhou P. R. China

A

Ayman Nafady

Department of Chemistry, College of Science

A

Abdullah M. Al‐Enizi

Department of Chemistry, College of Science King Saud University Riyadh Saudi Arabia

S

Shengqian Ma

Department of Chemistry