Single-Feature Identification of α2–8 Linked Sialoglycans Using Engineered Aerolysin Nanopores: A Paradigm for Glycan Linkage Analysis

J Jiaqi Li X Xinjia Zhao (State Key Laboratory of Phytochemistry and Natural Medicines) M Minmin Li (State Key Laboratory of Phytochemistry and Natural Medicines) W Wei Yu Y Yuting Li (Division of Chemical and Biological Sciences) C Chen Zhang (Shenzhen Institute for Quantum Science and Engineering, Department of Chemistry, and Department of Physics) H Hongzhi Cao (School of Medicine and Pharmacy) K Kan Zhong (School of Medicine and Pharmacy) J Jing Wang (Hunan Cancer Hospital Changsha China) Y Yuchen Cao (State Key Laboratory of Phytochemistry and Natural Medicines) X Xiaonong Li (Jiangxi Provincial Key Laboratory for Pharmacodynamic Material Basis of Traditional Chinese Medicine) H Han Zhou G Guoxiong Wang (State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics) X Xinmiao Liang (State Key Laboratory of Phytochemistry and Natural Medicines) G Guangyan Qing (State Key Laboratory of Phytochemistry and Natural Medicines)

Article Details

Volume / Issue Vol. 148, Issue 10
Published March 18, 2026
Pages 10649-10662
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (15)

J

Jiaqi Li

X

Xinjia Zhao

State Key Laboratory of Phytochemistry and Natural Medicines

M

Minmin Li

State Key Laboratory of Phytochemistry and Natural Medicines

W

Wei Yu

Y

Yuting Li

Division of Chemical and Biological Sciences

C

Chen Zhang

Shenzhen Institute for Quantum Science and Engineering, Department of Chemistry, and Department of Physics

H

Hongzhi Cao

School of Medicine and Pharmacy

K

Kan Zhong

School of Medicine and Pharmacy

J

Jing Wang

Hunan Cancer Hospital Changsha China

Y

Yuchen Cao

State Key Laboratory of Phytochemistry and Natural Medicines

X

Xiaonong Li

Jiangxi Provincial Key Laboratory for Pharmacodynamic Material Basis of Traditional Chinese Medicine

H

Han Zhou

G

Guoxiong Wang

State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics

X

Xinmiao Liang

State Key Laboratory of Phytochemistry and Natural Medicines

G

Guangyan Qing

State Key Laboratory of Phytochemistry and Natural Medicines