Nature Communications

Single-engineered-residue solvation perturbations regulate global protein architecture and function

Y Yingya Liu J Jihang Zhai (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Frontiers Science Center of Molecule Intelligent Syntheses, School of Chemistry and Molecular Engineering, East China Normal University 2 , Shanghai 200062,) S Shanshan Cao (Pingyuan Laboratory, School of Chemistry and Chemical Engineering) H Huiying Guo H Hengwei Zhang B Bo Song J Jiajia Guo (Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences) D Dong Men X Xiao He D Di Li (State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, 1 North 2nd Street, Zhongguancun, Haidian District, Beijing 100190, P. R. China)
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Article Details

Volume / Issue Vol. 17, Issue 1
Published March 10, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio
ISSN: 2041-1723 Open Access Life Sciences

Authors (10)

Y

Yingya Liu

J

Jihang Zhai

Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Frontiers Science Center of Molecule Intelligent Syntheses, School of Chemistry and Molecular Engineering, East China Normal University 2 , Shanghai 200062,

S

Shanshan Cao

Pingyuan Laboratory, School of Chemistry and Chemical Engineering

H

Huiying Guo

H

Hengwei Zhang

B

Bo Song

J

Jiajia Guo

Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences

D

Dong Men

X

Xiao He

D

Di Li

State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, 1 North 2nd Street, Zhongguancun, Haidian District, Beijing 100190, P. R. China

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