Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment

Julian Boutin; Sabrina Fayet; Victor Marin; Camille Bergès; Maude Riandière; Jérôme Toutain; Isabelle Lamrissi-Garcia; Chloé Thibault; David Cappellen; Sandrine Dabernat; Arthur Poulet; Maëla Francillette; Nathalie Droin; Christelle Debeissat; Philippe Brunet de la Grange; François Moreau-Gaudry; Aurélie Bedel

doi:10.1038/s41467-025-68177-3

Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment

J Julian Boutin S Sabrina Fayet V Victor Marin C Camille Bergès M Maude Riandière J Jérôme Toutain I Isabelle Lamrissi-Garcia C Chloé Thibault D David Cappellen S Sandrine Dabernat A Arthur Poulet M Maëla Francillette N Nathalie Droin C Christelle Debeissat P Philippe Brunet de la Grange F François Moreau-Gaudry A Aurélie Bedel

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published January 10, 2026

DOI 10.1038/s41467-025-68177-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

J

Julian Boutin

S

Sabrina Fayet

V

Victor Marin

C

Camille Bergès

M

Maude Riandière

J

Jérôme Toutain

I

Isabelle Lamrissi-Garcia

C

Chloé Thibault

D

David Cappellen

S

Sandrine Dabernat

A

Arthur Poulet

M

Maëla Francillette

N

Nathalie Droin

C

Christelle Debeissat

P

Philippe Brunet de la Grange

F

François Moreau-Gaudry

A

Aurélie Bedel

Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment

Article Details

Journal Info

Authors (17)

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