Simultaneous Degradation‐Depolymerization of Bioderived Comb Copolymers

M Megan E. Lott (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry) L Lucas M. Aburaya (George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA) R Rhys W. Hughes (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry) L Lauren E. Mann (George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA) J James B. Young (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry) C Cabell B. Eades (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry) F Florencia Merlino (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry) C Claire T. Su (George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA) B Brent S. Sumerlin (George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry)

Abstract

Abstract Poly(lactic acid) (PLA) is the most widely explored biodegradable alternative for polystyrene; however, its low toughness and glass transition temperature may limit its wider adoption as a sustainable replacement. To improve its material and thermal properties, PLA can be chemically or physically combined with other polymers, like poly(methyl methacrylate) (PMMA), though the incorporation of vinyl‐based polymer components complicates chemical recycling and reduces the sustainability of the material. In this study, we synthesized polymethacrylate‐PLA comb copolymers designed to be thermally deconstructed. Our design strategically extends current polymer deconstruction methodologies to more complex macromolecular systems. Thermally labile units within the polymethacrylate backbone permitted depolymerization that was concurrent with PLA side chain degradation during heating. This dual degradation‐depolymerization process enhances the overall sustainability of lactide/vinyl‐based copolymers and demonstrates the synergistic potential of integrating multiple deconstruction pathways into a single system. This report elaborates on the design of advanced, degradable copolymers, contributing to the further development of sustainable polymer materials.

Article Details

Volume / Issue Vol. 64, Issue 48
Published November 24, 2025
ISSN 1433-7851
Publisher Wiley

Journal Info

Angewandte Chemie International Edition

Wiley

ISSN: 1433-7851 Physical Sciences

Authors (9)

M

Megan E. Lott

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry

L

Lucas M. Aburaya

George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA

R

Rhys W. Hughes

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry

L

Lauren E. Mann

George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA

J

James B. Young

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry

C

Cabell B. Eades

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry

F

Florencia Merlino

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry

C

Claire T. Su

George & Josephine Butler Polymer Research Laboratory Center for Macromolecular Science & Engineering Department of Chemistry University of Florida PO Box 117200 Gainesville Florida 32611–7200 USA

B

Brent S. Sumerlin

George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry