Setmelanotide for the Treatment of Acquired Hypothalamic Obesity

J Jennifer L. Miller (Pediatric Endocrinology, Department of Pediatrics, College of Medicine, University of Florida, Gainesville) H Hanneke M. van Santen (Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands) S Susan A. Phillips (Rady Children’s Hospital, San Diego) J Jill Hamilton (Division of Endocrinology, Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto) J Jens Aberle (University Medical Center Hamburg–Eppendorf, Hamburg, Germany) T Thozhukat Sathyapalan (Hull York Medical School, Hull, United Kingdom) Z Zainaba Mohamed (Birmingham Women’s and Children’s, Birmingham, United Kingdom) S Shana E. McCormack (Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Philadelphia) A Ashley H. Shoemaker (Vanderbilt University Medical Center, Nashville) M Megan M. Kelsey (Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora) L Luma Ghalib (Ohio State Wexner Medical Center, Columbus) G Guenter Stalla (Medicover Neuroendokrinologie Medizinisches Versorgungszentrum, Münster, Germany) V Vidhu V. Thaker (Division of Molecular Genetics, Columbia University Irving Medical Center, New York) R Reema Habiby (Division of Endocrinology, Ann and Robert H. Lurie Children’s Hospital, Chicago) K Katie Larson Ode (Division of Pediatric Endocrinology and Diabetes, Stead Family Department of Pediatrics, University of Iowa, Iowa City) M Martin Wabitsch (Department of Pediatrics and Adolescent Medicine, Division of Pediatric Endocrinology and Diabetes, University Hospital Ulm, Ulm, Germany) M Mehul Dattani (Genetics and Genomic Medicine Programme, University College London Great Ormond Street Institute of Child Health, London) M M. Jennifer Abuzzahab (Children’s Minnesota, St. Paul) H Hussein Abdullatif (Department of Pediatric Endocrinology, University of Alabama, Birmingham) R Ryan Morgan (Lynn Health Science Institute, Oklahoma City) M Margaret Stefater-Richards (Division of Endocrinology, Boston Children’s Hospital, Boston) V Vanita R. Aroda (Brigham and Women’s Hospital, Boston) C Carsten Friedrich (University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg, Oldenburg, Germany) J Joan C. Han (Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Diabetes, Obesity, and Metabolism Institute, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York) H Hiraku Ono (Chiba University Hospital, Chiba, Japan) K Keisuke Nagasaki (Life Science Research Center, Nagano Children’s Hospital, Nagano, Japan) T Tomohiro Tanaka T Tsuyoshi Isojima (Department of Pediatrics, Toranomon Hospital, Tokyo) H Hiroshi Arima (Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan) C Cecilia Scimia (Rhythm Pharmaceuticals, Boston) G Guojun Yuan H Hermann L. Müller (University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg, Oldenburg, Germany) C Christian L. Roth (Seattle Children’s Research Institute, Norcliffe Foundation Center for Integrative Brain Research, Department of Pediatrics, University of Washington, Seattle)

Article Details

Volume / Issue Vol. 395, Issue 2
Published July 09, 2026
Pages 138-150
ISSN 0028-4793
Publisher Massachusetts Medical Society

Journal Info

New England Journal of Medicine

Massachusetts Medical Society

ISSN: 0028-4793 Social Sciences

Authors (33)

J

Jennifer L. Miller

Pediatric Endocrinology, Department of Pediatrics, College of Medicine, University of Florida, Gainesville

H

Hanneke M. van Santen

Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands

S

Susan A. Phillips

Rady Children’s Hospital, San Diego

J

Jill Hamilton

Division of Endocrinology, Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto

J

Jens Aberle

University Medical Center Hamburg–Eppendorf, Hamburg, Germany

T

Thozhukat Sathyapalan

Hull York Medical School, Hull, United Kingdom

Z

Zainaba Mohamed

Birmingham Women’s and Children’s, Birmingham, United Kingdom

S

Shana E. McCormack

Division of Endocrinology and Diabetes, Children’s Hospital of Philadelphia, Philadelphia

A

Ashley H. Shoemaker

Vanderbilt University Medical Center, Nashville

M

Megan M. Kelsey

Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora

L

Luma Ghalib

Ohio State Wexner Medical Center, Columbus

G

Guenter Stalla

Medicover Neuroendokrinologie Medizinisches Versorgungszentrum, Münster, Germany

V

Vidhu V. Thaker

Division of Molecular Genetics, Columbia University Irving Medical Center, New York

R

Reema Habiby

Division of Endocrinology, Ann and Robert H. Lurie Children’s Hospital, Chicago

K

Katie Larson Ode

Division of Pediatric Endocrinology and Diabetes, Stead Family Department of Pediatrics, University of Iowa, Iowa City

M

Martin Wabitsch

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Endocrinology and Diabetes, University Hospital Ulm, Ulm, Germany

M

Mehul Dattani

Genetics and Genomic Medicine Programme, University College London Great Ormond Street Institute of Child Health, London

M

M. Jennifer Abuzzahab

Children’s Minnesota, St. Paul

H

Hussein Abdullatif

Department of Pediatric Endocrinology, University of Alabama, Birmingham

R

Ryan Morgan

Lynn Health Science Institute, Oklahoma City

M

Margaret Stefater-Richards

Division of Endocrinology, Boston Children’s Hospital, Boston

V

Vanita R. Aroda

Brigham and Women’s Hospital, Boston

C

Carsten Friedrich

University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg, Oldenburg, Germany

J

Joan C. Han

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Diabetes, Obesity, and Metabolism Institute, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York

H

Hiraku Ono

Chiba University Hospital, Chiba, Japan

K

Keisuke Nagasaki

Life Science Research Center, Nagano Children’s Hospital, Nagano, Japan

T

Tomohiro Tanaka

T

Tsuyoshi Isojima

Department of Pediatrics, Toranomon Hospital, Tokyo

H

Hiroshi Arima

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan

C

Cecilia Scimia

Rhythm Pharmaceuticals, Boston

G

Guojun Yuan

H

Hermann L. Müller

University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg, Oldenburg, Germany

C

Christian L. Roth

Seattle Children’s Research Institute, Norcliffe Foundation Center for Integrative Brain Research, Department of Pediatrics, University of Washington, Seattle