Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer

Y Yapeng Su C ChunMei Liu (College of Science, Nanjing University of Posts and Telecommunications 1 , Nanjing 210023,) X Xiang Lu H Hui-Yu Chuang G Guideng Li S Shiqun Shao Y Yan Kong J Jihoon W. Lee R Rachel H. Ng S Stephanie Wong L Lidia Robert C Charles Warden V Victoria Liu J Jie Chen Z Zhuo Wang G Guangrong Qin Y Yin Tang (Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo and Biosensing, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University) H Hanjun Cheng A Alphonsus H. C. Ng D Daniel Chen S Songming Peng M Min Xue D Dazy Johnson Y Yu Xu J Jinhui Wang X Xiwei Wu I Ilya Shmulevich Q Qihui Shi R Raphael Levine A Antoni Ribas D David Baltimore J Jun Guo J James R. Heath W Wei Wei

Article Details

Volume / Issue Vol. 17, Issue 1
Published April 15, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (34)

Y

Yapeng Su

C

ChunMei Liu

College of Science, Nanjing University of Posts and Telecommunications 1 , Nanjing 210023,

X

Xiang Lu

H

Hui-Yu Chuang

G

Guideng Li

S

Shiqun Shao

Y

Yan Kong

J

Jihoon W. Lee

R

Rachel H. Ng

S

Stephanie Wong

L

Lidia Robert

C

Charles Warden

V

Victoria Liu

J

Jie Chen

Z

Zhuo Wang

G

Guangrong Qin

Y

Yin Tang

Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo and Biosensing, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University

H

Hanjun Cheng

A

Alphonsus H. C. Ng

D

Daniel Chen

S

Songming Peng

M

Min Xue

D

Dazy Johnson

Y

Yu Xu

J

Jinhui Wang

X

Xiwei Wu

I

Ilya Shmulevich

Q

Qihui Shi

R

Raphael Levine

A

Antoni Ribas

D

David Baltimore

J

Jun Guo

J

James R. Heath

W

Wei Wei