SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis

R Ren Luo M Min Yu K Kai Kang Y Yufeng Zhang S Shanghai Liu Z Zhuoran Yao Z Zichong Peng X Xuanwei Zhang S Shuangsi Liao Z Zhou Su L Linglu Yi H Hui Wang W Wenhao Zhao (Department of Biochemistry, Virginia Polytechnic Institute and State University) Y Yue Zheng (State Key Laboratory of Marine Environmental Science, College of the Environment and Ecology, Xiamen University) G Guo Lin R Ruizhan Tong F Feifei Na (Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) Y Youling Gong M Meijuan Huang (Division of Thoracic Tumor Multimodality Treatment and Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu) B Bingwen Zou L Long Bai R Renming Zhong D Di Yan G Gabriele Niedermann J Jianxin Xue (Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) Y You Lu (STFC Scientific Computing, Daresbury Laboratory)

Article Details

Volume / Issue Vol. 17, Issue 1
Published July 08, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (26)

R

Ren Luo

M

Min Yu

K

Kai Kang

Y

Yufeng Zhang

S

Shanghai Liu

Z

Zhuoran Yao

Z

Zichong Peng

X

Xuanwei Zhang

S

Shuangsi Liao

Z

Zhou Su

L

Linglu Yi

H

Hui Wang

W

Wenhao Zhao

Department of Biochemistry, Virginia Polytechnic Institute and State University

Y

Yue Zheng

State Key Laboratory of Marine Environmental Science, College of the Environment and Ecology, Xiamen University

G

Guo Lin

R

Ruizhan Tong

F

Feifei Na

Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

Y

Youling Gong

M

Meijuan Huang

Division of Thoracic Tumor Multimodality Treatment and Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu

B

Bingwen Zou

L

Long Bai

R

Renming Zhong

D

Di Yan

G

Gabriele Niedermann

J

Jianxin Xue

Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

Y

You Lu

STFC Scientific Computing, Daresbury Laboratory