SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues

X Xian-Xian Liu X Xuejuan Shen X Xinyuan Cui X Xiaoyuan Chen T Tengchuan Jin H Hua-Bin Cao X Xiaoman Lu M Mengyao Liu (State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College) L Li-Li Hu Y Yiting Chen X Xiao-Qing Chen Y Yang Zeng Y Yingde Gan X Xin Ou-Yang J Jie Lei (Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology) F Fa-Ying Liu F Fangting Chen Y Yang Zou Y Yongyi Shen

Article Details

Volume / Issue Vol. 17, Issue 1
Published April 13, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

X

Xian-Xian Liu

X

Xuejuan Shen

X

Xinyuan Cui

X

Xiaoyuan Chen

T

Tengchuan Jin

H

Hua-Bin Cao

X

Xiaoman Lu

M

Mengyao Liu

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

L

Li-Li Hu

Y

Yiting Chen

X

Xiao-Qing Chen

Y

Yang Zeng

Y

Yingde Gan

X

Xin Ou-Yang

J

Jie Lei

Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

F

Fa-Ying Liu

F

Fangting Chen

Y

Yang Zou

Y

Yongyi Shen