SamplingDesign: RNA design via continuous optimization with coupled variables and Monte-Carlo sampling

Wei Yu Tang; Ning Dai; Tianshuo Zhou; David H. Mathews; Liang Huang

doi:10.1038/s41467-025-67901-3

SamplingDesign: RNA design via continuous optimization with coupled variables and Monte-Carlo sampling

W Wei Yu Tang N Ning Dai (School of Physics and Optoelectronic Engineering, Hangzhou Institute for Advanced Study) T Tianshuo Zhou D David H. Mathews L Liang Huang (Research Center for Analytical Science, College of Chemistry)

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published February 20, 2026

DOI 10.1038/s41467-025-67901-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (5)

W

Wei Yu Tang

N

Ning Dai

School of Physics and Optoelectronic Engineering, Hangzhou Institute for Advanced Study

T

Tianshuo Zhou

D

David H. Mathews

L

Liang Huang

Research Center for Analytical Science, College of Chemistry

SamplingDesign: RNA design via continuous optimization with coupled variables and Monte-Carlo sampling

Article Details

Journal Info

Authors (5)

Related Articles from this Journal

Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants

Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain