Return to work among self-employed breast cancer survivors from the CANTO cohort

C Chloé Lopez I Idlir Licaj A Agnès Dumas J Julie Havas A Antonio Di Meglio I Ines Vaz Luis B Barbara Pistilli (Department of Cancer Medicine, Gustave Roussy, Villejuif, France) F Fabrice André A Anne-Laure Martin D Dominique Delmas C Christelle Jouannaud C Courèche Kaderbhai F François Cherifi M Mario Campone (Institut de Cancérologie de l’Ouest Angers-Nantes, Saint-Herblain, France) M Marie-Ange Mouret-Reynier (Centre Jean Perrin, Clermont-Ferrand, France) G Garazi Ruiz-de-Azua G Gwenn Menvielle

Abstract

Abstract The aim of this study was to assess return to work (RTW) after breast cancer (BC) by baseline employment status. Using data from the CANTO cohort (NCT01993498), we examined RTW among women below age 57 at BC diagnosis 2 and 4 years after BC diagnosis. We also assessed continuous work between years 2 and 4 post-diagnosis. Poisson regression models investigated associations between baseline employment (self-employed vs. employees) and RTW outcomes, adjusting for clinical, sociodemographic, and work-related factors and quality of life. We used education (above high school; high school or lower) as a proxy to further distinguish between white collar self-employees vs. blue collar self-employees (vs. employees). About 8% of women were self-employed at diagnosis. RTW was slightly higher among the self-employed compared to employees 2 years ( N  = 3178; PR = 1.04, 95%CI 0.98–1.10) and 4 years after diagnosis ( N  = 2329; PR = 1.05, 0.99–1.12). This effect was limited to white collar self-employed women. Among those who returned to work 2 years after diagnosis ( N  = 1683), self-employed women showed a 1.15 (1.01–1.31) higher prevalence of continuous work until year 4 post-diagnosis than employees. Self-employed women do not strongly differ from employees when assessing RTW at specific time points, however once returned to work, they experience fewer work interruptions than employees. This was observed in adjusted models, showing the intrinsic importance of job status in the RTW process. These findings highlight the importance of viewing RTW as an ongoing process, in order to provide appropriate and sustained support.

Article Details

Volume / Issue Vol. 16, Issue 1
Published March 12, 2026
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (17)

C

Chloé Lopez

I

Idlir Licaj

A

Agnès Dumas

J

Julie Havas

A

Antonio Di Meglio

I

Ines Vaz Luis

B

Barbara Pistilli

Department of Cancer Medicine, Gustave Roussy, Villejuif, France

F

Fabrice André

A

Anne-Laure Martin

D

Dominique Delmas

C

Christelle Jouannaud

C

Courèche Kaderbhai

F

François Cherifi

M

Mario Campone

Institut de Cancérologie de l’Ouest Angers-Nantes, Saint-Herblain, France

M

Marie-Ange Mouret-Reynier

Centre Jean Perrin, Clermont-Ferrand, France

G

Garazi Ruiz-de-Azua

G

Gwenn Menvielle