RETRACTION: An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

Abstract

RETRACTION : T. Yu, X. Liu, A.‐L. Bolcato‐Bellemin, Y. Wang, C. Liu, P. Erbacher, F. Qu, P. Rocchi, J.‐P. Behr, and L. Peng, “An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo,” Angewandte Chemie International Edition 51, no. 34 (2012): 8478‐8484. https://doi.org/10.1002/anie.201203920 . The above article, published online on 24 July 2012 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editors‐in‐Chief, Frank Maass and Nathalie Weickgenannt; the German Chemical Society; and Wiley‐VCH GmbH. A third party reported that Figure 1C contained duplicated bands, that the Naked siRNA bands in Figure 2D had been manipulated to remove data containing bands from the 0‐120 (min) lanes. These concerns were confirmed by the publisher. The authors responded to an inquiry by the publisher and stated that the bands in Figure 1C were original but agreed that Figure 2D was incorrect. The authors confirmed that all original data were no longer available, supplied data of repeated experiments for Figure 2D, and stated their intention to supply data from repeated experiments for Figure 1C. Both the editors and publisher agree that a correction with data from repeated experiments would not be appropriate. The retraction has been agreed to because the evidence of image manipulation in Figures 1C and 2D fundamentally compromises the editor's confidence in the conclusions presented in the article. The authors were informed of the retraction.