RETRACTED ARTICLE: A comprehensive explainable AI approach for enhancing transparency and interpretability in stroke prediction

M Marwa El-Geneedy H Hossam El-Din Moustafa H Hatem Khater S Seham Abd-Elsamee S Samah A. Gamel

Abstract

Abstract Stroke is among the leading causes of death, especially among old adults. Thus, the mortality rate and severe cerebral disability can be avoided when stroke is diagnosed at its early stages, followed by subsequent treatment. There is no doubt that healthcare specialists can find the necessary solutions more effectively and instantly with the help of artificial intelligence (AI) and machine learning (ML). In this study, we used ML classifiers and explainable artificial intelligence (XAI) to predict stroke. Six different ML classifiers that trained on available datasets for stroke patients. Six feature selection methodologies were used to extract essential features from the dataset. The XAI methods applied (Shapley Additive Values (SHAP), ELI5, and Local Interpretable Model-agnostic Explanations (LIME)). This study provides preliminary insights that may support the development of future tools to assist medical practitioners in managing patients, pending further clinical validation and real-world testing.

Article Details

Volume / Issue Vol. 15, Issue 1
Published July 18, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (5)

M

Marwa El-Geneedy

H

Hossam El-Din Moustafa

H

Hatem Khater

S

Seham Abd-Elsamee

S

Samah A. Gamel